On their way to Chicago for pizza, Marshall suggests they listen to something during the road trip. Ted mentions that he has a Jerky Boys CD in the car, but Lilly wants to listen to "Goodbye Sparky", a book on tape.

Marshall accidentally plays a Jerky Boys album to Lily's uterus.

The Family Guy pharmacist, Mort Goldman, is based on the character Sol Rosenberg by The Jerky Boys.