After agreeing to teach Bart Simpson himself, Superintendent Chalmers has a flashback to the last time he was a teacher. Chalmers walks in to the library of a school and asks if they are 'The Breakfast Club'. The kids tell him he's got it all wrong. They aren't 'The Breakfast Club', but they're the 'Fight Club'.

After returning home from the Teen Choice Awards on Meg's 18th birthday, Meg asks why there are so many cars parked on the street. Peter lets it slip that they are there for her surprise party. However, when the Griffins enter the front door, they see the house is empty. It turns out the cars are there because Mort is having a "Jewish Fight Club" where the first rule of Jewish Fight Club is that if someone says "Ow!", fight club is over.

George gets the idea to hide his herpes blister by being punched from Fight Club.

Bart makes the comment, "The first rule of Book Club..." a parody of the film 'Fight Club'.

The scene where Marshall is actively brawling with his brothers (especially the angle of his punching shot) is reminiscent of the brawling scenes from the movie Fight Club. It is also discussed in the Eriksen's Fight Club featurette in the Season 4 DVD set. Similarly Barney punching himself and then Ted is reminiscent of the main character's first fight with Tyler in 'Fight Club'.

In a flashback during his trial, Hank talks to the director of the film 'A Crazy Little Thing Called Love' which was based on his book, telling him the movie should've been "a little more Fight Club, a little less You've Got Mail.".

The clip of Edward Norton punching himself in the face is from Fight Club.

Megan wants to have a (girl) Fight Club-themed bachelorette party for Lillian, and even suggests busting out all her teeth because it will make it a memorable party.