Michael attempts to play the song on the guitar, while on the Booze Cruise.

Jake teaches Changpu to play 'Smoke on the Water' on his cello.

Ray's cousin Gerard is playing his accordion at the wedding vow renewal ceremony. He plays the song '(They Long to Be) Close to You' over and over, irritating Raymond. Ray asks if he can play something else, so Gerard begins to play the song 'Smoke on the Water'.

Homer listens to and sings this song after trying his medical marijuana for the first time.