The second part of City Slickers begins after the death of Curly. It is Mitch's 40th birthday, and his birthday is off to a good start, until he comes home to find his slacker brother, Glen, on his couch. Mitch is determined to have a romantic evening with his wife when he discovers a treasure map of Curly by chance. Together with Phil and Glen, he tries to find the hidden gold of Curly's father in the desert of Arizona instead of attending an important meeting in Las Vegas. They set out on an adventure together, full of surprises.