Winter
performed by Joshua Radin

The Gallaghers reel from the recent events of Monica's attempted suicide and Karen's birth. Jimmy gets back into Fiona's good graces and decides to let her meet his family. Frank plots to free Monica from the psychiatric institution but doesn't go according to plan when Monica reveals she has no plans to leave the institution and has found a new lover in a fellow patient (Jenna Elfman). Fiona finds a letter in the mail and it states she passed her GED and tells Lip in order to get him to finish school. After Jody and Sheila decide to keep Karen's newborn, Karen makes them choose between her and the baby since Karen wants nothing to do with it. When Sheila says she plans on raising her grandchild, Karen leaves but not without Lip saying she will regret the decision in the future. Ian discovers when meeting Jimmy's family that Ned, the man he slept with in the previous episode, is really Jimmy's doctor father, Lloyd. Estefania and Marco have a fight which results in her knocking on the Gallagher door for help in leaving Marco. After talking it over with Mandy about his recent events, Lip moves back home and brings his life back in order by going back to school.

While helping a patient regain his memory, the staff at Sacred Heart stir up some memories of their own. J.D., Elliot, Turk, Carla, Dr. Cox, Dr. Kelso and Janitor take a trip down memory lane in this clipshow of six years of Scrubs.

Jordan's siblings, Danni and Ben visit to celebrate Jack's first birthday. Carla tells Turk she will only take his last name if he has his mole removed. Dr. Cox is dismayed to learn that Ben has not been to a doctor for followup since his remission. Dr. Cox angrily blames J.D. for a patient's death and excuses him from his duties.