A family is involved in a car accident caused by a surgical intern from another hospital. The young pregnant wife has massive injuries and eventually dies, though Alex performs a Caesarean section to save the baby. Derek is angry at Meredith after he sees her at the vet's. Burke is angry at Cristina after she fell asleep during sex the previous night. George does not stand up for Callie to his roommates and Denny is becoming angry at being stuck in bed with no end in sight.