Having been kidnapped by a crazed Tuco, Walt and Jesse are held prisoner by him in a desert shack where he often hides out and takes care of his sick uncle. Walt's brother-in-law Hank and the DEA have rolled Tuco's entire organization, and Tuco thinks that his two prisoners may have been a source of information. Walt unsuccessfully tries to feed Tuco the poison he prepared. Hank meanwhile takes a bit of time off to look for Walt. Skyler is sick with worry and has been distributing handbills with Walt's photo. Hank remembers that Jesse Pinkman was Walt's source of marijuana and tries to track him down. Tuco finally realizes that his prisoners are up to something and it looks like he's going to kill Jesse. After a fight in which Tuco is shot, Hank shows up looking for Jesse.