Tom Jackman is plagued by strange transformations into a stronger, more animal-like version of himself. To ease the situation he hires an assistant in Katherine Reimer to see to the needs of both himself and his alter ego. He later finds that his estranged wife Claire has employed a detective, Miranda Calender, to find out why he left her. Calender is able to reveal to Jackman that he is apparently the last living descendant of Henry Jekyll, and that they look exactly alike, despite the fact that Jekyll never had children. She is unable to reveal who the other party observing him is. Meanwhile, Hyde continues to grow stronger as this third party introduces itself through Benjamin.