Nick and Hank discover a body that has floated down a river and had its eyes eaten by scavengers. The coroner says the cause of death was drowning, but that was because the body had lost so much blood, it had no strength to get out of the water. Their investigation leads them to a pair of homeless teens, Hansen (Daryl Sabara) and Gracie (Hannah Marks), who get money by selling shell necklaces that Gracie makes. The pair identify the body as their friend Stephen, who they say got a job and has not been around them lately. Nick and Hank go to a local clinic and ask if the doctors have seen Stephen. They say he was treated for a spider bite and has not checked back in. Nick and Hank are called to the scene of a car accident in which the driver was transporting human organs. Nick sees the man transfigure into a Geier. He questions Monroe about Geiers, a creature that removes organs from humans and them kills them. Monroe tells Nick that human organs are useful in many remedies for creatures, giving an example of how male testicles can cause a Viagra effect. Nick enlists Monroe's aid and Monroe goes to a local Fuchsbau, a fox-like apothacary, to see if any fresh organs have been transported. He purchases a vial of pure human gallbladder for Nick to analyze. Nick enters afterward and confronts the Fuchsbau, getting the phone number of the person delivering the organs. Nick and Julie take Gracie and Hansen to dinner and learn of another of their friends, Kevin, who also got a job with the same group as Stephen. They say all they know of it is they use white vans. After conversing with the Renard, he, Nick, Hank, and Wu head to the address retrieved from the phone number Nick got from the Fuchsbau. Meanwhile, Hansen and Gracie are kidnapped by men in a white van and taken to the organ removal site. When they arrive, Hansen uses Gracie's necklace to create a "trail of breadcrumbs". Nick and the police approach the address, a man busts out the window and is shot by Renard. The group enters to find a room full of human organs. The man's phone rings and Nick notices it is from the clinic. The group rushes to the clinic and Nick contronts a Geier who works there. She tells him where to find the kids. The police arrive at the organ removal site and notice the trail Hansen left. A gunfight ensues and Nick chases Dr. Levine (Valerie Cruz) the head surgeon outside. She attacks Nick from the trees and eventually falls into the giant fire pit formed outside. All of the kids are saved from the organ removal site. When Renard arrives back at the precinct, he has received a package from the Reapers. A phone call takes place in which the Reapers tell Renard he has to get rid of Nick or they will.