In autumn of 2003, 19-year-old Catherine Chandler's mother Vanessa was killed by two unknown hitmen; those men chased Catherine into the woods to kill her, too, where she was saved by a mysterious humanoid beast. In 2012, Catherine, now a successful New York police detective, is still plagued by memories of that mysterious beast as well as her mother's unsolved murder. "Cat" and her detective partner Tess are investigating the murder of blonde fashion editor Ashley Webster in a hotel. During the search, she finds fingerprints of deceased doctor Vincent Keller on the corpse. She learns that Keller was only helping Webster, whose death was the result of a previous poisoning. Ashley's husband Alex had been cheating on her; one of his mistresses killed his wife. Cat runs into Vincent as he again saves her during an attack by hired killers in a subway tunnel.