The series is about a teenage boy and his family who can transform into werewolves. Focusing on themes of coming of age and fitting in. While generally keeping true to the main ideas, this version made some changes from the film.
Scott Howard and his family live in the fictional town of Wolverton, a small town that draws tourists because of its history of werewolf sightings. Unlike the film, Scott's status as a werewolf is a secret.
Despite the youth audience, the cartoon series delivered very powerful critiques of disability-as-civil rights. Freely invoking an asthma attack or seizure the series centered on how Scott felt "weird" immediately before and during his werewolf transformation.
Although he never hurt anybody while he was a werewolf, Scott was conscious of his difference from other teenagers and had to make accommodations for himself. He also expressed frustration that the residents of this town had stereotyped "his people". A jock named Mick constantly picks on Scott for being the "outsider" at Wolverton High.