J.D.'s pregnant girlfriend, Kim, goes into labor as they begin to question their strength as a couple and as potential parents. Meanwhile, the rest of Sacred Heart team also seem to be having parenting issues, with Cox wondering whether to give his daughter an injection, Turk and Carla attempting to complete a video game so that they can focus on Izzy, and Kelso helping his son Harrison through a breakup. Dr. Cox works with a new group of interns.